The Science

The Thyroid Cure research references:

The functional mind/body approach introduced in The Thyroid Cure is backed up by the latest research in functional medicine, immunology, psychoneuroimmunology, epigenetics, nutrigenomics, toxicology and environmental studies.

We have included the endnotes online for easy reference.

Introductory Section

Amino N. Autoimmunity and hypothyroidism. Baillieres Clin Endocrinol Metab. 1988 Aug;2(3):591-617. http://www.ncbi.nlm.nih.gov/pubmed/3066320

Lipton B, Bhaerman S. Spontaneous Evolution Our Positive Future and a Way to Get There From Here. 3rd Edition. Hay House; 2010

American Autoimmune Related Diseases Association. Questions and Answers. http://www.aarda.org/autoimmune-information/questions-and-answers/

American Association of Clinical Endocrinologists. Hashimoto’s Thyroiditis. (2008) https://www.aace.com/files/hashimotos.pdf

“cure.” Dictionary.com Unabridged. Random House, Inc. http://dictionary.reference.com/browse/cure

Part One

Chapter 1

John Hopkins Medical. Autoimmune Disease Research. http://www.hopkinsmedicine.org/fox

American Autoimmune Related Diseases Association. Questions and Answers. http://www.aarda.org/autoimmune-information/questions-and-answers/

Chapter 2

Kornfeld R. The “New” Standard for Care in Medicine. Huffington Post. 12/2/2011 http://www.huffingtonpost.com/dr-robert-a-kornfeld/new-standard-medical-care_b_1117409.html

IMS Institute for Healthcare Informatics, The Use of Medicines in the United States: Review of 2010, http://www.imshealth.com/deployedfiles/imshealth/Global/Content/IMS%20Institute/Static%20File/IHII_UseOfMed_report.pdf

Centers for Medicare and Medicaid Services. National Health Expenditures 2011 Highlights. http://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/NationalHealthExpendData/downloads/highlights.pdf,

Herper M. The Best Selling Drugs in America. Forbes. 4/19/2011 http://www.forbes.com/sites/matthewherper/2011/04/19/the-best-selling-drugs-in-america/2/

Chapter 3

MacIntosh A. Understanding the Differences Between Conventional, Alternative, Complementary, Integrative and Natural Medicine. Townsend Letter, July 1999, http://tldp.com/medicine.htm

MacIntosh A. Understanding the Differences Between Conventional, Alternative, Complementary, Integrative and Natural Medicine. Townsend Letter, July 1999, http://tldp.com/medicine.htm

The National Center for Complementary and Alternative Medicine, NCCAM Facts-at-a-Glance and Mission, http://nccam.nih.gov/about/ataglance

Avik S. A. Roy, Senior Fellow, Manhattan Institute for Policy Research, Stifling New Cures: The True Cost of Lengthy Clinical Drug Trials, Project FDA Report No. 5 April 2012 http://www.manhattan-institute.org/html/fda_05.htm#01

MacIntosh A. Understanding the Differences Between Conventional, Alternative, Complementary, Integrative and Natural Medicine. Townsend Letter, July 1999, http://tldp.com/medicine.htm

Chapter 6

Eggleton P. Stress protein–polypeptide complexes acting as autoimmune triggers. Clin Exp Immunol. 2003 October; 134(1): 6–8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808840/

Stojanovich L, Marisavljevich D. Stress as a trigger of autoimmune disease. Autoimmun Rev. 2008 Jan;7(3):209-13. http://www.sciencedirect.com/science/article/pii/B9780123739476000477

Richardson B. DNA methylation and autoimmune disease. Clin Immunol. 2003 Oct;109(1):72-9. http://www.ncbi.nlm.nih.gov/pubmed/14585278

Ercolini A M, Miller S D. The role of infections in autoimmune disease. Clin Exp Immunol. 2009 January; 155(1): 1–15. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665673

Kivity S, Agmon-Levin N, Blank M, Shoenfeld Y. Infections and autoimmunity – friends or foes? Trends in Immunology – 1 August 2009 (Vol. 30, Issue 8, pp. 409-414) http://www.sciencedirect.com/science/article/pii/S1471490609001252

Velavan TP, Ojurongbe O. Regulatory T cells and parasites. J Biomed Biotechnol. 2011;201(1):520940. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255565/

Biagi F, Pezzimenti D, Campanella J, Corazza GR. Gluten exposure and risk of autoimmune disorders. Gut. 2002;51(1):140–141. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773261/

Negro R. Selenium and thyroid autoimmunity. Biologics. 2008 June; 2(2): 265–273. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721352/

Bigazzi P E. Autoimmunity and Heavy Metals. Lupus December 1994 vol. 3 no. 6 449-453 http://lup.sagepub.com/content/3/6/449.abstract

Orbach H, Agmon-Levin N, Zandman-Goddard G. Vaccines and autoimmune diseases of the adult. Discov Med. 2010 Feb;9(45):90-7. http://www.ncbi.nlm.nih.gov/pubmed/20193633

Vial T, Descotes J. Autoimmune diseases and vaccinations. Eur J Dermatol. 2004 Mar-Apr;14(2):86-90. http://www.ncbi.nlm.nih.gov/pubmed/15196997

Burek C L, Monica V. Talor M V. Environmental Triggers of Autoimmune Thyroiditis. J Autoimmun. 2009 Nov–Dec; 33(3-4): 183–189. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790188/

Akis M, Verhagen J, Taylor A, et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen specific T regulatory 1 and T helper 2 cells. J Exp Med 2004;199:1567-75

Rook GA, Brunet LR. Old friends for breakfast. Clin Exp Allergy 2005;35:841-2

Kidd P, Th1/Th2 Balance: The Hypothesis, its Limitations, and Implications for Health and Disease Alternative Medicine Review Vol. 8, Number 3 2003 (pp.223-246) http://www.altmedrev.com/publications/8/3/223.pdf

Rappaport S M, Smith M T. Environment and Disease Risks. Science 22 October 2010: Vol. 330 no. 6003 pp. 460-461 http://www.sciencemag.org/content/330/6003/460.summary

Chapter 7

Georgetown University Medical School. Thyroid Disease. http://medicine.georgetown.edu/divisions/endocrinology/knowledge/thyroid-disease

Weetman A. Review Article: Graves’ Disease. N Engl J Med Online. Oct. 2000 http://isites.harvard.edu/fs/docs/icb.topic442065.files/Endocrine_Readings/Graves_Disease.pdf

American Association of Clinical Endocrinologists. Hashimoto’s Thyroiditis. (2008) https://www.aace.com/files/hashimotos.pdf

Chapter 9

Sword R, Zimbardo P, Hurry Sickness; Is Our Quest to Do All and Be All Costing Us Our Health? Psychology Today Online Feb. 8, 2013 http://www.psychologytoday.com/blog/the-time-cure/201302/hurry-sickness

The American Institute of Stress (AIS) http://www.stress.org

Olpin N, Perceived Stress Levels and Sources of Stress Among College Students: Methods, Frequency, and Effectiveness of Managing Stress by College Students. Health Education PhD Dissertation. Southern Illinois University at Carbondale Mar. 29, 1996. http://faculty.weber.edu/molpin/dissertation.htm

Centers for Disease Control and Prevention. Crude and Age-Adjusted Percentage of Civilian, Non-institutionalized Population with Diagnosed Diabetes, United States, 1980–2011 http://www.cdc.gov/diabetes/statistics/prev/national/figage.htm

Kadiyala R, Peter R, Okosieme OE. Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies. Int J Clin Pract. 2010 Jul;64(8):1130-9 http://www.ncbi.nlm.nih.gov/pubmed/20642711

Hyman M. Why Your Genes Don’t Determine Your Health. Huffington Post Online. 01/01/11 http://www.huffingtonpost.com/dr-mark-hyman/human-genome_b_803069.html

Bronwell K.D. and Warner K.E. The Perils of Ignoring History: Big Tobacco Played Dirty and Millions Died. How Similar Is Big Food? The Milbank Quarterly, Vol. 87, No. 1, 2009 (pp. 259–294) http://www.yalerudds.org/resources/upload/docs/what/industry/Foodtobacco.pdf

Nordlee J, Taylor S, Townsend J, Thomas L, Bush R, Identification of A Brazil-Nut Allergen In Transgenic Soybeans. N Engl J Med 1996;334:688-92 http://genetica.ufcspa.edu.br/nutric/seminarios%20monitores/IDENTIFICATION_OF_A_BRAZIL-NUT_ALLERGEN_IN_TRANSGENIC_SOYBEANS%202008.pdf

Aris A, Leblanc S. Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada. Reprod Toxicol. 2011;31(4):528–533. http://www.sciencedirect.com/science/article/pii/S0890623811000566

Lin Z, Dongxia H, Xi C, et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA Cell Research. 2011;22:107–126 http://www.nature.com/cr/journal/v22/n1/full/cr2011158a.html

Miyake K, Tanaka T, McNeil PL Lectin-Based Food Poisoning: A New Mechanism of Protein Toxicity. PLoS ONE (2007) 2(8): e687. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000687

Cordain L., Toohey L., Smith M.J., Hickey M.S. Modulation of immune function by dietary lectins in rheumatoid arthritis. Br. J. Nutr. 2000;83:207–217 http://www.ncbi.nlm.nih.gov/pubmed/10884708

Jones L. Genetically modified foods. BMJ. 1999;318:581–584 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1115027/?report=reader#B14

Bishnoi S, Khetarpaul N, Yadav R. Effect of domestic processing and cooking methods on phytic acid and polyphenol contents of pea cultivars (Pisum sativum) Bishnoi S, Khetarpaul N, Yadav R. Effect of domestic processing and cooking methods on phytic acid and polyphenol contents of pea cultivars (Pisum sativum) Plant Foods for Human Nutrition June 1994, Volume 45, Issue 4, pp 381-388 http://link.springer.com/article/10.1007%2FBF01088088?LI=true#page-1

Tracy B. How did genetically altered wheat end up in Oregon field? CBS News June 6, 2013 http://www.cbsnews.com/8301-18563_162-57588150/how-did-genetically-altered-wheat-end-up-in-oregon-field/

Kasarda D, Can an Increase in Celiac Disease Be Attributed to an Increase in the Gluten Content of Wheat as a Consequence of Wheat Breeding? Journal of Agricultural and Food Chemistry 2013 61 (6), 1155-1159 http://pubs.acs.org/doi/full/10.1021/jf305122s#

Davis W. Is gluten on the increase? Blog Online. Feb. 15, 2013 http://www.wheatbellyblog.com/2013/02/is-gluten-on-the-increase/

Monetini L, Cavallo MG, Manfrini S, et al. Antibodies to bovine beta-casein in diabetes and other autoimmune diseases. Horm Metab Res. 2002 Aug;34(8):455-9 http://www.ncbi.nlm.nih.gov/pubmed/12198602

US Dept. Of Agriculture. Genetically engineered varieties of corn, upland cotton, and soybeans, by State and for the Unites States, 2000-13. http://www.ers.usda.gov/data-products/adoption-of-genetically-engineered-crops-in-the-us.aspx#.Ua58DGTb1bs

Bray G, Nielsen S, Popkin B. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr 2004 79: 4 537-543 http://ajcn.nutrition.org/content/79/4/537.abstract

Dufault R, LeBlanc B, Schnoll R, et al. Mercury from chlor-alkali plants: measured concentrations in food product sugar. Environmental Health. 2009;8:2. http://www.ncbi.nlm.nih.gov/pubmed/19171026

Siegmund B, Leitner E, Pfannhauser W. Determination of the nicotine content of various edible nightshades (solanaceae) and their products and estimation of the associated dietary nicotine intake. J Agric Food Chem 1999;47:3113–20 http://www.ncbi.nlm.nih.gov/pubmed/10552617

US Dept. Of Agriculture. Genetically engineered varieties of corn, upland cotton, and soybeans, by State and for the Unites States, 2000-13. http://www.ers.usda.gov/data-products/adoption-of-genetically-engineered-crops-in-the-us.aspx#.Ua58DGTb1bs

Doerge D, Sheehan D. Goitrogenic and Estrogenic Activity of Soy Isoflavones. Environmental Health Perspectives. v110 June 2002. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241182/pdf/ehp110s-000349.pdf

Persky VW, Turyk ME, Wang L, et al. Effect of soy protein on endogenous hormones in postmenopausal women. Am J Clin Nutr 2002;75:145-153. http://ajcn.nutrition.org/content/75/1/145.abstract

Asthma and Allergy Foundation of America. Peanut Allergy. Updated 2005 http://www.aafa.org/display.cfm?id=9&sub=20&cont=517

Kritchevsky D, Tepper SA, Klurfeld DM. Lectin may contribute to the atherogenicity of peanut oil. Lipids. 1998;33:821–3. http://www.ncbi.nlm.nih.gov/pubmed/9727614

Pramod SN, Venkatesh YP, Mahesh PA. Potato lectin activates basophils and mast cells of atopic subjects by its interaction with core chitobiose of cell-bound non-specific immunoglobulin E. Clin Exp Immunol. 2007;148:391–401. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941928/

Singh R, Subramanian S, Rhodes JM, Campbell BJ. Peanut lectin stimulates proliferation of colon cancer cells by interaction with glycosylated CD44v6 isoforms and consequential activation of c-Met and MAPK: functional implications for disease-associated glycosylation changes. Glycobiology.2006;16:594–601 http://glycob.oxfordjournals.org/content/16/7/594.full

Sategna-Guidetti C, Volta U, Ciacci C, et al. Prevalence of thyroid disorders in untreated adult celiac disease patients and effect of gluten withdrawal: an Italian multicenter study. American Journal of Gastroenterology. 2001;96(3):751–757. http://www.ncbi.nlm.nih.gov/pubmed/11280546

Brown A.C. Gluten Sensitivity, Problems of an Emerging Condition Separate From Celiac Disease Expert Rev Gastroenterol Hepatol. 2012;6(1):43-55. http://www.ncbi.nlm.nih.gov/pubmed/22149581

Tucková L, Tlaskalová-Hogenová H, Farré MA, et al. Molecular mimicry as a possible cause of autoimmune reactions in celiac disease? Antibodies to gliadin cross-react with epitopes on enterocytes. Department of Immunology and Gnotobiology, First Faculty of Medicine, Prague, Czech Republic. Clinical Immunology and Immunopathology [1995, 74(2):170-176 http://www1.lf1.cuni.cz/~kocna/docum/cs_tucko.pdf

Miyake K, Tanaka T, McNeil PL. Lectin-Based Food Poisoning: A New Mechanism of Protein Toxicity. PLoS ONE (2007) 2(8): e687. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000687

Fasano A. Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer. Physiol Rev. Vol 91. Jan 2011. 151175 http://www.ncbi.nlm.nih.gov/pubmed/21248165

Fasano A. Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall. Am J Pathol. 2008;173:1243–1252.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570116/

Arrieta MC, Bistritz L, Meddings JB, Alterations in intestinal permeability. Gut. 55: 1512–1520 (2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856434/pdf/1512.pdf

Ulluwishewa D, Anderson RC, Mcnabb WC, Moughan PJ, Wells JM, Roy NC. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141:769–76 http://jn.nutrition.org/content/141/5/769.full

Mishra A, Liu S, Sams G. H, et al. Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation. Cancer Cell, 2012; 22 (5): 645 http://www.cell.com/cancer-cell/abstract/S1535-6108(12)00394-7

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Inadera H. The immune system as a target for environmental chemicals: xenoestrogens and other compounds. Toxicol Letters 2006;164: 191–206 http://www.ncbi.nlm.nih.gov/pubmed/16697129

Ahmed SA, Hissong BD, Verthelyi D, Donner K, Becker K, Karpuzoglu-Sahin E. Gender and risk of autoimmune diseases: possible role of estrogenic compounds. Environ Health Perspect. 1999;107 (Suppl 5):681–686. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566250/

Straub RH. 2007. The complex role of estrogens in inflammation. Endocr. Rev. 28: 521–574 http://edrv.endojournals.org/content/28/5/521.full

Mayes M, Epidemiologic studies of environmental agents and systemic autoimmune diseases. Environmental Health Perspectives 11/1999; 107 Suppl 5:743-8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566245/pdf/envhper00522-0088.pdf

Weidler C, Härle P, Schedel J, Schmidt M, Schölmerich J, Straub RH. Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens. J Rheumatol 31:489–494 2004 http://www.jrheum.org/content/31/3/489.short

Vedhara K, Cox NK, Wilcock GK, et al. Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination. Lancet. 1999 Feb 20;353(9153):627–31 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166443/

Miller GE, Cohen S, Ritchey AK. Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model. Health Psychol 2002; 21: 531–541. http://www.ncbi.nlm.nih.gov/pubmed/12433005

Abou-Donia MB, El-Masry EM, Abdel-Rahman AA, McLendon RE, Schiffman SS. Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats. J Toxicol Environ Health A 71:1415–1429 2008. http://www.ncbi.nlm.nih.gov/pubmed/18800291

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Yurino H, Ishikawa S, Sato T, Akadegawa K, Ito T, Ueha S, et al. Endocrine disruptors (environmental estrogens) enhance autoantibody production by B1 cells. Toxicol Sci. 2004;81:139–47 http://www.ncbi.nlm.nih.gov/pubmed/15166399

Richter CA, Birnbaum LS, Farabollini F, Newbold RR, Rubin BS, et al. In vivo effects of bisphenol A in laboratory rodent studies. Reprod Toxicol 2007; 24: 199–224. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151845/

Ye X, Bishop AM, Reidy JA, Needham LL, Calafat AM. Parabens as urinary biomarkers of exposure in humans. Environ Health Perspect. 2006a;114:1843–1846. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764178/

Menegaux F, Baruchel A, Bertrand Y, et al. Household exposure to pesticides and risk of childhood acute leukaemia. Occupational and Environmental Medicine. 2006;63(2):131–134. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078075/

Zhang Y, Guo GL, Han X, et al. Do polybrominated diphenyl ethers (PBDE) increase the risk of thyroid cancer? Bioscience Hypotheses. 2008;1(4):195–199 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612591/figure/F1/

Zhang Y, Guo GL, Han X, et al. Do polybrominated diphenyl ethers (PBDE) increase the risk of thyroid cancer? Bioscience Hypotheses. 2008;1(4):195–199 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612591/

Yi J, Cao J. Tea and fluorosis. Journal of Fluorine Chemistry 129:1976-81. (2008).

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Braathen M, Derocher AE, Wiig O, Sormo EG, Lie E, Skaare JU, Jenssen BM. Relationships between PCBs and thyroid hormones and retinol in female and male polar bears. Environ Health Perspect. 2004;112:826–833 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242008/

Schiraldi M., Monestier M. How can a chemical element elicit complex immunopathology? Lessons from mercury-induced autoimmunity. (2009) Trends Immunol. 30, 502–509. http://toxcenter.org/artikel/Quecksilber-crasht-Autoimmunitaet.pdf

Exley C, Begum A, Woolley MP, Bloor RN. Aluminum in tobacco and cannabis and smoking-related disease. Am. J. Med. 2006;119:276 e9–276 http://www.ncbi.nlm.nih.gov/pubmed/16490479

Tomljenovic L. Aluminum and Alzheimer’s disease: after a century of controversy, is there a plausible link? J Alzheimers Dis. 2011;23:567–598 http://www.ncbi.nlm.nih.gov/pubmed/21157018

Sterzl I, Procházková J, Hrda P, Matucha P, Bartova J, Stejskal V. Removal of dental amalgam decreases anto-TPO and anti-Tg autoantibodies in patients with autoimmune thyroiditis. Neuro Endocrinol Lett. 2006;5(27(Suppl 1):25–30 http://www.ncbi.nlm.nih.gov/pubmed/16804512

Geier D, Kern J, Garver C, et al. Biomarkers of environmental toxicity and susceptibility in autism, Journal of the Neurological Sciences, Volume 280, Issues 1–2, 15 May 2009, Pages 101-10 http://www.sciencedirect.com/science/article/pii/S0022510X08004310

Shoenfeld Y, Agmon-Levin N. ‘ASIA’ – autoimmune/inflammatory syndrome induced by adjuvants. J Autoimmun. 2011;11:4–8 http://www.ncbi.nlm.nih.gov/pubmed/20708902?dopt=Abstract&holding=f1000,f1000m,isrctn

Tomljenovic L, Shaw CA. Aluminum Vaccine Adjuvants: Are they Safe? Curr Med Chem. 2011;18:2630–2637 http://www.ncbi.nlm.nih.gov/pubmed/21568886

Tomljenovic L, Shaw CA. Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations. Lupus February 2012 21: 223-230 http://lup.sagepub.com/content/21/2/223

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Cherry JD. Why do pertussis vaccines fail? Pediatrics 129: 968–970 (2012)

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Orenstein WA, Heseltine PN, LeGagnoux SJ, Portnoy B. Rubella vaccine and susceptible hospital employees. Poor physician participation. JAMA. 1981 Feb 20;245(7):711–713 http://www.ncbi.nlm.nih.gov/pubmed/7463660

Part Two

Chapter 12

The American Academy of Clinical Endocrinologists www.aacc.org/SiteCollectionDocuments/NACB/LMPG/…/3c_thyroid.doc

American Association of Clinical Endocrinologists. Over 13 Million Americans with Thyroid Disease Remain Undiagnosed. January 2003 Press Release. http://www.hospitalsoup.com/public/AACEPress_release-highlighted.pdf

Chapter 13

Takasu N, Komiya I, Asawa T, Nagasawa Y, Yamada T. Test for recovery from hypothyroidism during thyroxine therapy in Hashimoto’s thyroiditis. Lancet. 1990;336(8723):1084–6 http://www.ncbi.nlm.nih.gov/pubmed/1977978

Takasu N, Komiya I, Asawa T, Nagasawa Y, Yamada T. Test for recovery from hypothyroidism during thyroxine therapy in Hashimoto’s thyroiditis. Lancet. 1990;336(8723):1084–6 http://www.ncbi.nlm.nih.gov/pubmed/1977978

Chapter 14

Intahphuak S, Khonsung P, Panthong A. Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil. Pharmaceutical Biology. 2010;48(2):151–157 http://www.ncbi.nlm.nih.gov/pubmed/20645831

Takahashi M, Inoue S, Hayama K, Ninomiya K, Abe S. Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitoro and its therapeutic efficacy in murine oral candidiasis. Med Mycol J. 2012;53(4):255-61. http://www.ncbi.nlm.nih.gov/pubmed/23257726

Reger MA, Henderson ST, Hale C. Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiol Aging. 2004 Mar;25(3):311-4 http://www.ncbi.nlm.nih.gov/pubmed?term=Neurobiol%20Aging.%202004%20Mar;25(3):311-4

St-Onge MP, Jones PJ. Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J Nutr. 2002 Mar;132(3):329-32. http://www.ncbi.nlm.nih.gov/pubmed/11880549?dopt=Abstract

Bergsson G, Arnfinnsson J, Ólafur Steingrı́msson, Thormar H. In Vitro Killing of Candida albicans by Fatty Acids and Monoglycerides. Antimicrob. Agents Chemother. November 2001 vol. 45 no. 11 3209-3212 http://aac.asm.org/content/45/11/3209.full

Boyages S. Progress in Understanding the Clinical Consequences of Endemic Iodine Deficiency. Current Opinion in Endocrinology, Diabetes and Obesity 4.5 (1997): 320-327. http://www.researchgate.net/publication/232133920_Progress_in_understanding_the_clinical_consequences_of_endemic_iodine_deficiency

Keck AS, Finley JW. Cruciferous Vegetables: Cancer Protective Mechanisms of Glucosinolate Hydrolysis Products and Selenium. Integr Cancer Ther March 2004 3: 5-12 http://www.ncbi.nlm.nih.gov/pubmed/15035868 –

Barrera LN, Cassidy A, Wang W, et al. TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research. Oct 2012, Vol. 1823, No. 10: 1914-192 http://www.ncbi.nlm.nih.gov/pubmed/22820176

Chapter 15

Kaushik RM, Kaushik R, Mahajan SK, Rajesh V. Effects of mental relaxation and slow breathing in essential hypertension. Complement Ther Med. 2006;14:120–6. http://www.complementarytherapiesinmedicine.com/article/S0965-2299(05)00148-2/fulltext

National Sleep Foundation. Annual Sleep in America Poll Exploring Connections with Communications Technology Use and Sleep. Published Online. March 7, 2011. http://www.sleepfoundation.org/article/press-release/annual-sleep-america-poll-exploring-connections-communications-technology-use-

National Sleep Foundation. How Much Sleep Do Adults Need? http://www.sleepfoundation.org/article/white-papers/how-much-sleep-do-adults-need

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Part Three

Viljoen M, Panzer A, Roos J.L, Bodemer W. Psychoneuroimmunology: From Philosophy, Intuition and Folklore to a Recognized Science. South African Journal of Science 99 July/August 2003: 332. http://connection.ebscohost.com/c/articles/11532011/psychoneuroimmunology-from-philosophy-intuition-folklore-recognized-science

Viljoen M, Panzer A, Roos J.L, Bodemer W. Psychoneuroimmunology: From Philosophy, Intuition and Folklore to a Recognized Science. South African Journal of Science 99 July/August 2003: 332. http://connection.ebscohost.com/c/articles/11532011/psychoneuroimmunology-from-philosophy-intuition-folklore-recognized-science

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Lawler K. A., Younger J. W., Piferi R. L., Jobe R. L., Edmondson K. A., Jones W. H. (2005). The unique effects of forgiveness on health: an exploration of pathways. J.Behav. Med. 28, 157–167. http://www.ncbi.nlm.nih.gov/pubmed/15957571

Lawler K. A., Younger J. W., Piferi R. L., Jobe R. L., Edmondson K. A., Jones W. H. (2005). The unique effects of forgiveness on health: an exploration of pathways. J.Behav. Med. 28, 157–167. http://www.ncbi.nlm.nih.gov/pubmed/15957571